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Koichi Tsuneyama Selected Research

Cholates

1/2022A Novel Mouse Model of Nonalcoholic Steatohepatitis Suggests that Liver Fibrosis Initiates around Lipid-Laden Macrophages.
3/2021Development of a novel mouse model of diet-induced nonalcoholic steatohepatitis-related progressive bridging fibrosis.
1/2013Eicosapentaenoic acid attenuates hepatic accumulation of cholesterol esters but aggravates liver injury and inflammation in mice fed a cholate-supplemented high-fat diet.

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Koichi Tsuneyama Research Topics

Disease

46Inflammation (Inflammations)
07/2022 - 08/2002
40Neoplasms (Cancer)
05/2022 - 10/2003
40Biliary Liver Cirrhosis (Primary Biliary Cirrhosis)
01/2022 - 08/2002
31Non-alcoholic Fatty Liver Disease
06/2022 - 10/2006
24Fibrosis (Cirrhosis)
06/2022 - 12/2003
23Cholangitis
01/2022 - 08/2007
19Obesity
09/2021 - 02/2008
18Carcinogenesis
06/2022 - 09/2006
17Hepatocellular Carcinoma (Hepatoma)
12/2021 - 03/2005
16Chemical and Drug Induced Liver Injury
11/2019 - 09/2009
15Carcinoma (Carcinomatosis)
01/2022 - 02/2003
14Fatty Liver
09/2021 - 10/2006
13Neoplasm Metastasis (Metastasis)
05/2022 - 09/2006
13Body Weight (Weight, Body)
11/2021 - 10/2006
13Metabolic Syndrome (Dysmetabolic Syndrome X)
11/2021 - 03/2010
12Liver Cirrhosis (Hepatic Cirrhosis)
03/2022 - 01/2006
11Autoimmune Diseases (Autoimmune Disease)
12/2021 - 01/2003
10Alcoholic Fatty Liver
03/2022 - 03/2008
9Insulin Resistance
06/2022 - 11/2009
9Liver Diseases (Liver Disease)
06/2021 - 11/2009
9Type 2 Diabetes Mellitus (MODY)
12/2018 - 02/2008
7Colitis
01/2022 - 03/2009
7Cholangiocarcinoma
12/2021 - 02/2003
7Infections
10/2019 - 08/2007
6Adenoma (Adenomas)
01/2022 - 11/2006
5Necrosis
01/2018 - 01/2004
5Wounds and Injuries (Trauma)
01/2018 - 01/2012
5Hypersensitivity (Allergy)
01/2017 - 03/2010
5Hyperlipidemias (Hyperlipidemia)
01/2017 - 01/2011
5Adenocarcinoma
12/2007 - 09/2006
4Disease Progression
01/2022 - 01/2012
4Chronic Hepatitis C
12/2021 - 04/2006
4Cholestasis
12/2019 - 07/2003
4Diabetes Mellitus
11/2019 - 09/2009
4Hepatitis
01/2014 - 02/2010
4Inflammatory Bowel Diseases (Inflammatory Bowel Disease)
01/2014 - 06/2008
4Squamous Cell Carcinoma (Epidermoid Carcinoma)
06/2011 - 01/2002
4Stomach Neoplasms (Stomach Cancer)
12/2007 - 09/2006
4Lymphatic Metastasis
01/2007 - 09/2006
3Polyps
01/2022 - 05/2014
3Virus Diseases (Viral Diseases)
12/2021 - 10/2011
3Hyperglycemia
09/2021 - 04/2013
3Type 1 Diabetes Mellitus (Autoimmune Diabetes)
09/2021 - 07/2014
3Lymphoma (Lymphomas)
05/2021 - 01/2013
3Lung Neoplasms (Lung Cancer)
01/2021 - 12/2007
3Pancreatic Neoplasms (Pancreatic Cancer)
01/2019 - 03/2009

Drug/Important Bio-Agent (IBA)

23Pharmaceutical PreparationsIBA
03/2021 - 09/2009
22CytokinesIBA
01/2022 - 01/2003
20Proteins (Proteins, Gene)FDA Link
10/2021 - 07/2003
14AntibodiesIBA
01/2022 - 06/2008
13CholesterolIBA
01/2022 - 07/2003
12AutoantibodiesIBA
01/2022 - 01/2003
12Sodium Glutamate (Accent)IBA
02/2020 - 02/2008
11LipidsIBA
01/2022 - 01/2006
9Biomarkers (Surrogate Marker)IBA
07/2022 - 01/2012
9Messenger RNA (mRNA)IBA
11/2019 - 03/2004
8MucinsIBA
01/2017 - 10/2002
7DNA (Deoxyribonucleic Acid)IBA
10/2019 - 01/2005
7Interleukin-17 (Interleukin 17)IBA
12/2018 - 02/2009
7AntigensIBA
12/2018 - 03/2004
6ChemokinesIBA
01/2021 - 09/2005
6Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
12/2016 - 09/2006
6InterleukinsIBA
06/2014 - 11/2009
6Transforming Growth Factor beta Receptors (TGF beta Receptors)IBA
10/2012 - 06/2008
6Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
02/2010 - 06/2008
5Transforming Growth Factors (Transforming Growth Factor)IBA
06/2022 - 02/2013
5Glutamate-Ammonia Ligase (Glutamine Synthetase)IBA
09/2021 - 06/2014
5MicroRNAs (MicroRNA)IBA
12/2020 - 01/2012
5Bile Acids and Salts (Bile Acids)IBA
01/2019 - 02/2012
5EnzymesIBA
05/2018 - 10/2009
5Interferon-gamma (Interferon, gamma)IBA
01/2018 - 06/2008
5Insulin (Novolin)FDA Link
09/2017 - 10/2006
5Chemokine ReceptorsIBA
01/2017 - 11/2002
5Glucose (Dextrose)FDA LinkGeneric
03/2016 - 03/2008
5Receptor for Advanced Glycation End ProductsIBA
04/2013 - 10/2005
4AutoantigensIBA
01/2022 - 03/2008
4Choline (Choline Chloride)IBA
12/2021 - 01/2012
4Indicators and Reagents (Reagents)IBA
12/2021 - 09/2006
4Streptozocin (Streptozotocin)FDA Link
09/2021 - 07/2014
4LigandsIBA
01/2021 - 06/2007
4Volatile Fatty AcidsIBA
02/2020 - 01/2017
4Small Interfering RNA (siRNA)IBA
01/2019 - 08/2007
4Immunoglobulins (Immunoglobulin)IBA
10/2014 - 10/2005
4Acetaminophen (Paracetamol)FDA LinkGeneric
08/2014 - 01/2004
4XenobioticsIBA
08/2014 - 08/2007
4Interleukin-12 (IL 12)IBA
06/2014 - 10/2012
4Galectin 3 (LGALS3)IBA
01/2012 - 01/2006
4Tumor Viral Antigens (Large T Antigen)IBA
04/2008 - 01/2007
3CollagenIBA
03/2022 - 10/2002
3CholatesIBA
01/2022 - 01/2013
3Methionine (L-Methionine)FDA Link
12/2021 - 12/2013
3OligosaccharidesIBA
11/2021 - 01/2017
3Blood Glucose (Blood Sugar)IBA
11/2021 - 09/2017
3Fatty Acids (Saturated Fatty Acids)IBA
01/2021 - 05/2012
3Cholic AcidIBA
11/2019 - 02/2012
3CarcinogensIBA
11/2019 - 02/2007
3OsteopontinIBA
07/2018 - 01/2003

Therapy/Procedure

19Therapeutics
07/2022 - 01/2006
18Drug Therapy (Chemotherapy)
12/2021 - 10/2009
4Kampo Medicine (Kampo)
10/2012 - 03/2008